Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Radial Expansion Facilitates the Maintenance of Double Antibiotic Resistances.

Antimicrobial agents and chemotherapy - 20 Aug 2020

Durão Paulo, Ramiro Ricardo S, Pereira Cátia, Jurič Jernej, Pereira Delfina, Gordo Isabel

Abstract excerpt

Most microbes live in spatially confined subpopulations. Under spatial structure conditions, the efficacy of natural selection is often reduced (relative to homogeneous conditions) due to the increased importance of genetic drift and local competition. Additionally, under spatial structure conditions, the fittest genotype may not always be the one with better access to the heterogeneous distribution of nutrients....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Escherichia coli Proteins

Share to Fluoroquinolones

Share to Mutation

Share to Rifampin

Share to Streptomycin

Source

Open in PubMed Open full text

Identifiers

PMID: 32540973
DOI: 10.1128/AAC.00668-20
PMCID: PMC7449181

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Radial Expansion Facilitates the Maintenance of Double Antibiotic Resistances.PMID 32540973Read ↗

Evolutionary Mechanisms Shaping the Maintenance of Antibiotic Resistance.Semantic proximity Read ↗

Environmental heterogeneity facilitates competitive suppression of drug resistanceSemantic proximity Read ↗

Spatial drug asymmetry modulates phenotypic diversity-migration relationships under resistance evolutionSemantic proximity Read ↗

On the rapidity of antibiotic resistance evolution facilitated by a concentration gradientSemantic proximity Read ↗

Pervasive genotype-by-environment interactions shape the fitness effects of antibiotic resistance mutations.Semantic proximity Read ↗

Timing of antibiotic administration determines the spread of plasmid-encoded antibiotic resistance during microbial range expansion.Semantic proximity Read ↗

Determinants of Genetic Diversity of Spontaneous Drug Resistance in Bacteria.Semantic proximity Read ↗

Antibiotic Resistance Increases Evolvability and Maximizes Opportunities Across Fitness LandscapesSemantic proximity Read ↗

Spatial structure inhibits the rate of invasion of beneficial mutations in asexual populations.Semantic proximity Read ↗

Multidrug-resistant bacteria compensate for the epistasis between resistances.Semantic proximity Read ↗

Polyclonal pathogen populations accelerate the evolution of antibiotic resistance in patientsSemantic proximity Read ↗

Bacterial motility governs the evolution of antibiotic resistance in spatially heterogeneous environmentsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.