Article
Not Indolamine 2,3-Dioxygenase Polymorphisms, but Low Levels of Indoleamine 2,3-Dioxygenase and IDO2 Are Associated with Behçet's Syndrome.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre - 1 Jan 2025
Oral Haluk Barbaros, Uçar Ülkü, Atalay Yağmur Aydın, Özkaya Güven, Oral Haluk Barbaros
Abstract excerpt
<p>Objective: Behçet's syndrome (BS) is a multisystemic disorder with a complex genetic background. Indoleamine 2,3-dioxygenase (IDO) and IDO2, key enzymes in tryptophan metabolism, have immunomodulatory effects. Specific IDO and IDO2 polymorphisms may influence enzymatic activity. This study aimed to explore the association between IDO/IDO2 gene polymorphisms and BS susceptibility, and assess serum levels of IDO...
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