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Article

A cross-tissue transcriptome-wide association study reveals novel susceptibility genes for erectile dysfunction.

Andrology - 1 Jan 2026

Zhu Tianle, Ma Yukuai, Yang Peng, Cao Zhi, Gao Jingjing, Du Junhua, Gao Pan, Jiang Hui, Zhang Xiansheng

Abstract excerpt

BACKGROUND: Erectile dysfunction (ED) is a common condition affecting millions of men worldwide. While genome-wide association studies (GWAS) have identified genetic loci associated with ED risk, the potential causative genes and their biological mechanisms leading to ED remain largely unexplored. OBJECTIVES: This study aimed to conduct a comprehensive cross-tissue transcriptome-wide association study (TWAS) to...

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Source

Identifiers

PMID: 40145662
DOI: 10.1111/andr.70034

Genes

LCLAT1
CPT1B
CSF2RB
DNAH7
EHD3
L3MBTL2
MDH1B
REEP1
SLC30A6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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