Article
Improving predictive models for Alzheimer's disease using GWAS data by incorporating misclassified samples modeling.
PloS one - 1 Jan 2020
Romero-Rosales Brissa-Lizbeth, Tamez-Pena Jose-Gerardo, Nicolini Humberto, Moreno-Treviño Maria-Guadalupe, Trevino Victor
Abstract excerpt
Late-onset Alzheimer's Disease (LOAD) is the most common form of dementia in the elderly. Genome-wide association studies (GWAS) for LOAD have open new avenues to identify genetic causes and to provide diagnostic tools for early detection. Although several predictive models have been proposed using the few detected GWAS markers, there is still a need for improvement and identification of potential markers....
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