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Identification of a New FtsZ Inhibitor by Virtual Screening, Mechanistic Insights, and Structure–Activity Relationship Analyses

18 Mar 2025

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide Antimicrobial resistance (AMR) poses a major threat to human health globally. Approximately 5 million deaths were attributed to AMR in 2019, and this figure is predicted to worsen, reaching 10 million deaths by 2050. In the search for new compounds that can tackle AMR, FtsZ inhibitors represent a valuable option. In the present study, a structure-based virtual...

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PMID: 40100965
DOI: 10.1021/acsinfecdis.4c01045

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