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Article

Association of cardiovascular-kidney-metabolic health and apolipoprotein E4 genotype with risk of dementia and mortality.

Journal of Alzheimer's disease : JAD - 1 Apr 2025

Huang Xinghe, Liang Jie, Zhang Junyu, Fu Jiayi, Chen Yige, Xie Wuxiang, Zheng Fanfan

Abstract excerpt

BackgroundPoor cardiovascular-kidney-metabolic (CKM) health is becoming prevalent; however, sparse data exist regarding the association of CKM health with incident dementia and all-cause mortality.ObjectiveThis study aimed to examine whether poor CKM health is associated with a higher risk of dementia and all-cause mortality, regardless of APOE4 carrier status.MethodsIn this prospective cohort study, 352,364...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40095665
DOI: 10.1177/13872877251324093

Genes

CKM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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