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Article

Education and Cardiovascular Health as Effect Modifiers of APOE ε4 on Dementia: The Atherosclerosis Risk in Communities Study.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Jun 2022

Lee Mark, Hughes Timothy M, George Kristen M, Griswold Michael E, Sedaghat Sanaz, Simino Jeannette, Lutsey Pamela L

Abstract excerpt

BACKGROUND: Both education and cardiovascular risk factors are strongly associated with dementia risk. However, it is not clear whether these associations persist or vary among individuals with high genetic risk for Alzheimer's disease. We examined the interactive relationship between lifestyle and genetic dementia risk factors in a prospective cohort study. METHODS: Our data came from the Atherosclerosis Risk in...

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Identifiers

PMID: 34614170
DOI: 10.1093/gerona/glab299
PMCID: PMC9159668

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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