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Clinical and Genetic Factors Associated with Neuroendocrine Neoplasms: A UK Biobank Study.

Neuroendocrinology - 1 Jan 2025

Green Harry David, El-Asmar Marie Line, Rous Brian, Hawkes Gareth, Moreno-Montilla Maria Trinidad, Thirlwell Christina, Ramage John

Abstract excerpt

INTRODUCTION: Incidence of neuroendocrine neoplasms (NENs) is rising globally, yet clinical and genetic factors remain poorly understood. Evidence for the role of obesity is conflicted, and studies on prospectively collected data are sparse. We aimed to identify clinical and germline genetic risk factors associated with NEN in the UK Biobank. METHODS: Cases of NEN were identified in the UK Biobank's cancer...

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PMID: 40081351
DOI: 10.1159/000545114

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