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Article

Germline Cancer Testing in Unselected Patients With Neuroendocrine Neoplasms: A Multicenter Prospective Study.

Pancreas - 1 Sept 2026

Abidoye Oluseyi, Golafshar Michael, Kunz Katie, Eslinger Cody, Elsabbagh Zaid, Alheraki Samee Z, Alsulaiman Abdullah, Klint Margaret, Esplin Edward, Nussbaum Robert L, Starr Jason, Ahn Daniel, Bekaii-Saab Tanios, Halfdanarson Thorvardur, Samadder Niloy J, Sonbol Mohamad B

Abstract excerpt

PURPOSE: Neuroendocrine neoplasms (NENs) are increasingly recognized to have a hereditary predilection, yet the prevalence and clinical relevance of pathogenic germline variants (PGVs) in unselected patients with NEN remain poorly defined. This prospective, multicenter study aimed to evaluate the prevalence and clinical utility of PGVs through universal multigene panel testing in a diverse cohort of patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42240119
DOI: 10.1097/MPA.0000000000002665

Genes

CHEK2
MEN1
MITF
MLH1
MSH2
MSH6
MUTYH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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