Gut microbiota and type 1 diabetes: a two-sample bidirectional Mendelian randomization study

Abstract excerpt

Objective The real causal relationship between human gut microbiota and T1D remains unclear and difficult to establish. Herein, we adopted a two-sample bidirectional mendelian randomization (MR) study to evaluate the causality between gut microbiota and T1D. Methods We leveraged publicly available genome-wide association study (GWAS) summary data to perform MR analysis. The gut microbiota-related GWAS data from...

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• Clostridium difficile and Clostridium perfringens research
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