Article
Divide and conquer approach for genome-wide association studies.
Genetics - 17 Apr 2025
Özkaraca Mustafa İsmail, Agung Mulya, Navarro Pau, Tenesa Albert
Abstract excerpt
Genome-wide association studies (GWAS) are computationally intensive, requiring significant time and resources with computational complexity scaling at least linearly with sample size. Here, we present an accurate and resource-efficient pipeline for GWAS that mitigates the impact of sample size on computational demands. Our approach involves (1) randomly partitioning the cohort into equally sized sub-cohorts, (2)...
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