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Article

Catecholaminergic Polymorphic Ventricular Tachycardia: Advancing From Molecular Insights to Preclinical Models.

Journal of the American Heart Association - 18 Mar 2025

Schneider Luca, Begovic Merima, Zhou Xiaobo, Hamdani Nazha, Akin Ibrahim, El-Battrawy Ibrahim

Abstract excerpt

Inherited cardiac channelopathies are linked to a heightened risk of sudden cardiac death. Despite evolving knowledge on different genes for these inherited conditions, for certain subtypes, such as catecholaminergic polymorphic ventricular tachycardia syndrome, the specific genetic causes remain unidentified. The research of the pathophysiological mechanisms underlying catecholaminergic polymorphic ventricular...

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Identifiers

PMID: 40079282
DOI: 10.1161/JAHA.124.038308
PMCID: PMC12132699

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