Article
Gene Therapy for Catecholaminergic Polymorphic Ventricular Tachycardia.
Heart, lung & circulation - 1 Jul 2023
Pérez Paloma Remior, Hylind Robyn J, Roston Thomas M, Bezzerides Vassilios J, Abrams Dominic J
Abstract excerpt
Over the last three decades, the genetic basis of various inherited arrhythmia syndromes has been elucidated, providing key insights into cardiomyocyte biology and various regulatory pathways associated with cellular excitation, contraction, and repolarisation. As varying techniques to manipulate genetic sequence, gene expression, and different cellular pathways have become increasingly defined and understood,...
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