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Updates on inherited arrhythmia syndromes (Brugada syndrome, long QT syndrome, CPVT, ARVC).

Progress in cardiovascular diseases - 1 Jan 2025

Moore Benjamin M, Roston Thomas M, Laksman Zachary, Krahn Andrew D

Abstract excerpt

The inherited arrhythmia (IA) syndromes are a group of rare and complex conditions that may predispose individuals to ventricular arrhythmias and sudden cardiac death. Our understanding of the genetic architecture underlying these syndromes has evolved, with recent reappraisals of variant pathogenicity and quantification of polygenic influences. The IA population includes an increasing proportion of low-risk...

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Identifiers

PMID: 40505939
DOI: 10.1016/j.pcad.2025.06.002

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