Integrated multi-omic analysis and experiment reveals the role of endoplasmic reticulum stress in lung adenocarcinoma

Abstract excerpt

BACKGROUND: Lung cancer is a highly prevalent malignancy worldwide and is associated with high mortality rates. While the involvement of endoplasmic reticulum (ER) stress in the development of lung adenocarcinoma (LUAD) has been established, the underlying mechanism remains unclear. METHODS: In this study, we utilized data from The Cancer Genome Atlas (TCGA) to identify differentially expressed endoplasmic...

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