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Advances in cfDNA research for pregnancy-related diseases

5 Aug 2025

Abstract excerpt

Circulating cell-free DNA (cfDNA) comprises extracellular DNA fragments released into bodily fluids through cellular processes such as apoptosis, necrosis, and active secretion. Alterations in cfDNA concentration, fragmentation patterns, and molecular characteristics under physiological and pathological conditions, including pregnancy-related disorders, have established its value as a minimally invasive biomarker...

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PMID: 40837189
DOI: 10.3389/fcell.2025.1600532

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