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Article

SIRT3/6: an amazing challenge and opportunity in the fight against fibrosis and aging

31 Jan 2024

Abstract excerpt

Fibrosis is a typical aging-related pathological process involving almost all organs, including the heart, kidney, liver, lung, and skin. Fibrogenesis is a highly orchestrated process defined by sequences of cellular response and molecular signals mechanisms underlying the disease. In pathophysiologic conditions associated with organ fibrosis, a variety of injurious stimuli such as metabolic disorders, epigenetic...

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PMID: 38294557
DOI: 10.1007/s00018-023-05093-z

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