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Article

Refining prognostic stratification of atypical meningiomas: significance of chromosome 1p deletion and brain invasion

6 Mar 2025

Abstract excerpt

Atypical meningiomas display heterogeneous clinical outcomes, necessitating prognostic markers to identify cases that would benefit of adjuvant treatment. This study investigated the prognostic value of chromosome 1p deletion, assessed by fluorescent in situ hybridization (FISH), in a cohort of 98 primary atypical meningiomas. The accuracy of FISH was validated by comparison with next-generation sequencing (NGS)...

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PMID: 40050905
DOI: 10.1186/s40478-025-01973-6

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