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Article

Human leukocyte antigen variation is associated with cytomegalovirus serostatus in healthy individuals.

American journal of human genetics - 3 Apr 2025

Boquett Juliano A, Sauter Jürgen, Schmidt Alexander H, Maiers Martin, Hollenbach Jill A

Abstract excerpt

Cytomegalovirus (CMV) is a common β-herpes virus worldwide with an estimated seroprevalence among the general population of 83%. Primary infection is usually benign; however, CMV can cause severe morbidity in newborns in whom it is acquired congenitally, as well as immunocompromised individuals. Understanding the role of immunogenetic variation in risk for CMV infection can provide insight into the immune control...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 40049169
DOI: 10.1016/j.ajhg.2025.02.007
PMCID: PMC12081270

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