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Genomic and geographical structure of human cytomegalovirus

17 Jul 2023

Abstract excerpt

Human cytomegalovirus (CMV) has infected humans since the origin of our species and currently infects most of the world's population. Variability between CMV genomes is the highest of any human herpesvirus, yet large portions of the genome are conserved. Here, we show that the genome encodes 74 regions of relatively high variability each with 2 to 8 alleles. We then identified two patterns in the CMV genome....

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PMID: 37459519
DOI: 10.1073/pnas.2221797120

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