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The Subventricular Zone in Glioblastoma: Genesis, Maintenance, and Modeling

10 Mar 2022

Abstract excerpt

Glioblastoma (GBM) is a malignant tumor with a median survival rate of 15-16 months with standard care; however, cases of successful treatment offer hope that an enhanced understanding of the pathology will improve the prognosis. The cell of origin in GBM remains controversial. Recent evidence has implicated stem cells as cells of origin in many cancers. Neural stem/precursor cells (NSCs) are being evaluated as...

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PMID: 35359410
DOI: 10.3389/fonc.2022.790976

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