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Circulating tumor DNA in clinical trials for solid tumors: Challenges and current applications

29 Aug 2023

Abstract excerpt

Tumor derived biomarkers including circulating tumor DNA (ctDNA) and/or circulating tumors cells (CTCs) may be detected and quantified through liquid biopsy (LB). ctDNA analysis through LB is a validated tool for monitoring response to systemic treatment and detecting molecular mechanisms of resistance at the time of progression of advanced stage malignancies. Several applications of ctDNA have been investigated...

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PMID: 40027283
DOI: 10.1016/j.jlb.2023.100007

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