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Liquid Biopsy: Approaches to Dynamic Genotyping in Cancer

1 Jan 2017

Abstract excerpt

Malignant tumors release tumor cells and fragments of nucleic acids into the bloodstream. Liquid biopsies are non-invasive blood tests that detect circulating tumor cells (CTC) and circulating nucleic acids such as mRNA, microRNA, and cell-free circulating tumor DNA, also known as ctDNA. The presence of ctDNA or CTCs in the plasma has prognostic impact. Since ctDNA contains tumor-specific mutations, its detection...

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PMID: 28693026
DOI: 10.1159/000478864

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