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Article

Circulating Tumor DNA as a Liquid Biopsy for Cancer

12 Nov 2014

Abstract excerpt

BACKGROUND: Targeted therapies have markedly changed the treatment of cancer over the past 10 years. However, almost all tumors acquire resistance to systemic treatment as a result of tumor heterogeneity, clonal evolution, and selection. Although genotyping is the most currently used method for categorizing tumors for clinical decisions, tumor tissues provide only a snapshot, or are often difficult to obtain. To...

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Identifiers

PMID: 25388429
DOI: 10.1373/clinchem.2014.222679

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