Article
High risk surveillance MRI may not be necessary in BRCA1/2 mutation carriers over 70 years old.
Breast cancer research and treatment - 1 Jun 2025
Botty van den Bruele Astrid, Ren Yi, Thomas Samantha M, Ntowe Koumani W, Rosenberger Laura H, Menendez Carolyn, Grimm Lars J, Chiba Akiko, Plichta Jennifer K
Abstract excerpt
BACKGROUND: The risk of developing breast cancer up to age 80 for women with BRCA1/2 mutations is approximately 69-72%. The risk estimates, however, become labile in the later years of life. Many older BRCA1/2 mutation carriers who have not developed breast cancer continue to undergo high-risk surveillance. We evaluated breast cancers in women age ≥ 70 and identified which modality diagnosed the malignancy....
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