MRI Surveillance and Breast Cancer Mortality in Women With BRCA1 and BRCA2 Sequence Variations.

doi:10.1001/jamaoncol.2023.6944

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Article

MRI Surveillance and Breast Cancer Mortality in Women With BRCA1 and BRCA2 Sequence Variations.

JAMA oncology - 1 Apr 2024

Lubinski Jan, Kotsopoulos Joanne, Moller Pal, Pal Tuya, Eisen Andrea, Peck Larissa, Karlan Beth Y, Aeilts Amber, Eng Charis, Bordeleau Louise, Foulkes William D, Tung Nadine, Couch Fergus J, Fruscio Robert, Ramon Y Cajal Teresa, Singer Christian F, Neuhausen Susan L, Zakalik Dana, Cybulski Cezary, Gronwald Jacek, Huzarski Tomasz, Stempa Klaudia, Dungan Jeffrey, Cullinane Carey, Olopade Olufunmilayo I, Metcalfe Kelly, Sun Ping, Narod Steven A

Abstract excerpt

Importance: Magnetic resonance imaging (MRI) surveillance is offered to women with a pathogenic variant in the BRCA1 or BRCA2 gene who face a high lifetime risk of breast cancer. Surveillance with MRI is effective in downstaging breast cancers, but the association of MRI surveillance with mortality risk has not been well defined. Objective: To compare breast cancer mortality rates in women with a BRCA1 or BRCA2...

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Identifiers

PMID: 38421676
DOI: 10.1001/jamaoncol.2023.6944
PMCID: PMC10905376

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