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The Impact of Human Salivary Amylase Gene Copy Number and Starch on Oral Biofilms

19 Feb 2025

Abstract excerpt

The copy number (CN) variant AMY1 encodes the salivary amylase enzyme which promotes starch digestion. Although this gene has been associated with dental caries and periodontal disease susceptibility, the impact of the interaction between AMY1 CN and starch on oral biofilms is unclear. We explored how oral microbiota communities shaped by AMY1 CN respond to starch by employing an in vitro model of biofilm...

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PMID: 40005827
DOI: 10.3390/microorganisms13020461

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