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Article

Adjuvanted subunit intranasal vaccine reduces SARS-CoV-2 onward transmission in hamsters

7 Feb 2025

Abstract excerpt

Introduction: Most COVID-19 vaccine trials have focused on recipient protection, not protection of their contacts, a critical need. As a subunit intranasal COVID-19 vaccine reduced nasopharyngeal virus more than did an intramuscular (IM) vaccine, we hypothesized that this vaccine might reduce onward transmission to others. Methods: We vaccinated hamsters with either the IM-administrated licensed mRNA vaccine...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 39981227
DOI: 10.3389/fimmu.2025.1514845

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

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