Article

mRNA-1273 efficacy in a severe COVID-19 model: attenuated activation of pulmonary immune cells after challenge

2021-01-25

Abstract excerpt

<h4>ABSTRACT</h4> The mRNA-1273 vaccine was recently determined to be effective against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from interim Phase 3 results. Human studies, however, cannot provide the controlled response to infection and complex immunological insight that are only possible with preclinical studies. Hamsters are the only model that reliably exhibit more severe SARS-CoV-2 disea...

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Literature Corpus work: 85bf5369-1500-503b-b89a-c9403b98b010
DOI: 10.1101/2021.01.25.428136

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