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A live attenuated influenza virus-vectored intranasal COVID-19 vaccine provides rapid, prolonged, and broad protection against SARS-CoV-2 infection

2021-11-15

Abstract excerpt

Remarkable progress has been made in developing intramuscular vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); however, they are limited with respect to eliciting local immunity in the respiratory tract, which is the primary infection site for SARS-CoV-2. To overcome the limitations of intramuscular vaccines, we constructed a nasal vaccine candidate based on an influenza vector by ins...

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Identifiers and source

Literature Corpus work
4a1789e0-989c-5640-a4a8-e148d514f40a
DOI
10.1101/2021.11.13.468472
Open publication

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A live attenuated influenza virus-vectored intranasal COVID-19 vaccine provides rapid, prolonged, and broad protection against SARS-CoV-2 infectionDOI 10.1101/2021.11.13.468472
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