Article

Infection- or vaccine mediated immunity reduces SARS-CoV-2 transmission, but increases competitiveness of Omicron in hamsters

2022-07-29

Abstract excerpt

Omicron has demonstrated a competitive advantage over Delta in vaccinated people. To understand this, we designed a transmission chain experiment using naïve, intranasally (IN) or intramuscularly (IM) vaccinated, and previously infected (PI) hamsters. Vaccination and previous infection protected animals from disease and virus replication after Delta and Omicron dual challenge. A gradient in transmission blockage w...

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Literature Corpus work: 01dcf01c-0253-5cbd-92aa-0a1e3b6021e7
DOI: 10.1101/2022.07.29.502072

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