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Article

Epigenetic regulation in alcoholic liver disease

1 Jan 2011

Abstract excerpt

Alcoholic liver disease (ALD) is characterized by steatosis or fat deposition in the liver and inflammation, which leads to cirrhosis and hepatocellular carcinoma. Induction of target genes without involving changes in DNA sequence seems to contribute greatly to liver injury. Chromatin modifications including alterations in histones and DNA, as well as post-transcriptional changes collectively referred to as...

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Alcohol Consumption and Health Effects
Endoplasmic Reticulum Stress and Disease
Genomics, phytochemicals, and oxidative stress

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 21633650
DOI: 10.3748/wjg.v17.i20.2456

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