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Article

Detection of diverse HIV strains by the m-PIMATM HIV-1/2 detect point-of-care assay.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Apr 2025

Anderson Mark, Teodoro Lara, Harley Fiona, Almaraz Eduardo, Vallari Ana, Strobel Carolyn, Harris Barbara, Meyer Todd V, Ndembi Nicaise, Mbanya Dora, James Linda, Mboup Souleymane, Plantier Jean-Christophe, Cloherty Gavin, Rodgers Mary

Abstract excerpt

BACKGROUND: HIV displays exceptionally high virus diversity that can impact detection by diagnostic assays, which rely on sequence conservation. METHODS: We tested the m-PIMA HIV-1/2 Detect point-of-care (POC) assay (Abbott Rapid Diagnostics) against a diverse HIV panel of 340 serum/plasma specimens and diluted cultured virus isolates for which viral load (VL) and classified sequences were known, including HIV-1...

Read the complete abstract on PubMed

Topics

Humans
HIV Infections
HIV-1
HIV-2
Sensitivity and Specificity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Point-of-Care Testing

Viral Load

Point-of-Care Systems

Genetic Variation

Source

Identifiers

PMID: 39954305
DOI: 10.1016/j.jcv.2025.105771

Provenance

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