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ARCHITECT HIV Combo Ag/Ab and RealTime HIV-1 Assays Detect Diverse HIV Strains in Clinical Specimens.

AIDS research and human retroviruses - 1 Mar 2018

Rodgers Mary A, Vallari Ana S, Yamaguchi Julie, Holzmayer Vera, Harris Barbara, Toure-Kane Coumba, Mboup Souleymane, Badreddine Samar, McArthur Carole, Ndembi Nicaise, Mbanya Dora, Kaptue Lazare, Cloherty Gavin

Abstract excerpt

Periodic evaluation of the impact of viral diversity on diagnostic tests is critical to ensure current technologies are keeping pace with viral evolution. To determine whether HIV diversity impacts the ARCHITECT HIV Combo Ag/Ab (HIV Combo) or RealTime HIV-1 (RT) assays, a set of N = 199 HIV clinical specimens from Cameroon, Senegal, Saudi Arabia, and Thailand were sequenced and tested in both assays. The panel...

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Identifiers

PMID: 29232958
DOI: 10.1089/AID.2017.0244
PMCID: PMC5863103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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