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Article

Causal effects of cardiovascular risk factors on onset of major age-related diseases: A time-to-event Mendelian randomization study.

Experimental gerontology - 1 Jul 2018

He Liang, Culminskaya Irina, Loika Yury, Arbeev Konstantin G, Bagley Olivia, Duan Matt, Yashin Anatoliy I, Kulminski Alexander M

Abstract excerpt

BACKGROUNDS: Elucidating the causal effects of common intermediate risk factors on the onset of age-related diseases is indispensable for developing prevention and intervention procedures. METHODS: We conducted two-stage time-to-event Mendelian randomization meta-analyses combining five large-scale longitudinal cohorts to investigate dynamic causal effects of cardiovascular disease risk factors including body...

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Identifiers

PMID: 28964830
DOI: 10.1016/j.exger.2017.09.019
PMCID: PMC5874182

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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