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Physical Activity, Genetic Susceptibility, and Risk of Colorectal Cancer in Type 2 Diabetes: A Large Population-Based Cohort Study.

Deutsches Arzteblatt international - 4 Apr 2025

Wu Yanjun, Meng Meijun, Liu Yufeng, Zeng Ruijie, Feng Jing, Lian Qizhou, Ma Yuying, Zhang Lijun, Huang Wentao, Leung Felix W, Duan Chongyang, Sha Weihong, Chen Hao

Abstract excerpt

BACKGROUND: It is crucial to identify modifiable preventive measures to mitigate the risk of colorectal cancer (CRC) among patients with type 2 diabetes (T2D), a high-risk group for CRC. We conducted a study to investigate the potential association between various levels of physical activity (PA) and the incidence of CRC, taking account of genetic susceptibility, in a T2D population cohort. METHODS: The study was...

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PMID: 39936588
DOI: 10.3238/arztebl.m2025.0013
PMCID: PMC12504870

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