Association between accelerometer-measured physical activity, genetic risk, and incident type 2 diabetes: A prospective cohort study.

doi:10.1111/dom.70166

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Article

Association between accelerometer-measured physical activity, genetic risk, and incident type 2 diabetes: A prospective cohort study.

Diabetes, obesity & metabolism - 1 Dec 2025

Pan Yang, Zhang Wenya, Dai Yiwen, Liu Yuling, Gao Darui, Zhang Yanyu, Ma Jingya, Zhu Menghan, Diao Xuyang, Yang XinQing, Ji Mengmeng, Xie Wuxiang, Zheng Fanfan

Abstract excerpt

AIMS: To evaluate the dose-response relationship between the time spent on different types of physical activity and incident type 2 diabetes (T2D), and whether genetic risk would modify this relationship. MATERIALS AND METHODS: Based on data from 93,096 participants without T2D at baseline from the UK Biobank, we calculated hazard ratios (HRs) between accelerometer-measured physical activity, including sedentary...

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Topics

Humans
Diabetes Mellitus, Type 2
Male
Female
Exercise
Middle Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Accelerometry

Prospective Studies

Sedentary Behavior

Genetic Predisposition to Disease

Aged

Incidence

United Kingdom

Risk Factors

Sleep

Adult

Source

Open in PubMed

Identifiers

PMID: 41039941
DOI: 10.1111/dom.70166

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LIPA

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