Molecular detection of mecA gene from methicillin-resistant Staphylococcus aureus isolated from clinical and environmental samples and its potential inhibition by phytochemicals using in vitro and in silico approach

Abstract excerpt

Abstract The increasing prevalence of Methicillin-resistant Staphylococcus aureus (MRSA) has posed significant challenges in clinical and environmental settings. MRSA's resistance is attributed to the mecA gene, which encodes the penicillin-binding protein 2a (PBP2a), conferring resistance to β-lactam antibiotics. This study aimed to molecularly detect the mecA gene in MRSA isolates from clinical and...

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