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Targeted inhibition of mecA and agrA genes in clinical MRSA isolates by natural bioactive compounds

26 Aug 2025

Abstract excerpt

Introduction Methicillin-resistant Staphylococcus aureus (MRSA) colonization in the nasal nares significantly contributes to hospital-acquired infections. This poses a global health concern due to its resistance to β-lactam antibiotics and its virulence mediated by quorum sensing (QS). This study investigates the antimicrobial efficacy of two natural bioactive compounds (BACs)—curcumin and eugenol—against...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40933137
DOI: 10.3389/fmicb.2025.1643774

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