Article
Multiscale Synergy Networks Offer Insights into Disease and Comorbidity Mechanisms.
Analytical chemistry - 18 Feb 2025
Wang Yongpei, Zhu Zeyu, Deng Lingli, Cheng Kian-Kai, Guo Fanjing, Lin Genjin, Raftery Daniel, Dong Jiyang
Abstract excerpt
Complex diseases involve extensive metabolic interactions within intricate biological networks. Consequently, it is advantageous to analyze metabolic phenotype data through metabolite interactions rather than focus on individual metabolites in isolation. In this article, we propose a novel analysis strategy called SynNet, which constructs multiscale synergy networks associated with specific metabolic phenotypes,...
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