Article
Parental bias in expression and interaction of genes in the equine placenta.
Proceedings of the National Academy of Sciences of the United States of America - 20 Apr 2021
Dini Pouya, Kalbfleisch Theodore, Uribe-Salazar José M, Carossino Mariano, Ali Hossam El-Sheikh, Loux Shavahn C, Esteller-Vico Alejandro, Norris Jamie K, Anand Lakshay, Scoggin Kirsten E, Rodriguez Lopez Carlos M, Breen James, Bailey Ernest, Daels Peter, Ball Barry A
Abstract excerpt
Most autosomal genes in the placenta show a biallelic expression pattern. However, some genes exhibit allele-specific transcription depending on the parental origin of the chromosomes on which the copy of the gene resides. Parentally expressed genes are involved in the reciprocal interaction between maternal and paternal genes, coordinating the allocation of resources between fetus and mother. One of the main...
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