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Article

Assessment of cardiac iron deposition and genotypic classification in pediatric beta-thalassemia major: the role of cardiac MRI.

BMC medical imaging - 30 Jan 2025

Zhang Siqi, Zhao Wen, Sun Longwei, Liang Guohua, Wang Xiaodong, Zeng Hongwu

Abstract excerpt

BACKGROUND: Beta thalassemia major (β-TM) is a severe genetic anemia with considerable phenotypic heterogeneity. This study investigated whether genotype correlates with distinct myocardial iron overload patterns, assessed by cardiovascular magnetic resonance (CMR) T2* values. METHODS: CMR data for cardiac iron deposition evaluation, which recruited pediatric participants between January 2021 and December 2024,...

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Identifiers

PMID: 39885407
DOI: 10.1186/s12880-025-01567-7
PMCID: PMC11783902

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