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Understanding metastasis mixed-treatment responses through genomic analyses

30 Jan 2025

Abstract excerpt

Early-stage and metastatic breast cancers (MBC) can exhibit genomic heterogeneity, even within the same individual. Response to therapy in metastatic breast cancer patients with multiple metastases can also be heterogeneous, with different degrees of responsiveness to the same drug(s) across metastatic sites, termed "mixed response," within the same patient. Whether this treatment response variability is...

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PMID: 39885167
DOI: 10.1038/s41523-025-00724-z

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