Article
Genomic landscape of extraordinary responses in metastatic breast cancer.
Communications biology - 9 Apr 2021
Lim Sun Min, Kim Eunyoung, Jung Kyung Hae, Kim Sora, Koo Ja Seung, Kim Seung Il, Park Seho, Park Hyung Seok, Park Byoung Woo, Cho Young Up, Kim Ji Ye, Paik Soonmyung, Kwon Nak-Jung, Kim Gun Min, Kim Ji Hyoung, Kim Min Hwan, Jeon Min Kyung, Kim Sangwoo, Sohn Joohyuk
Abstract excerpt
Extreme responders to anticancer therapy are rare among advanced breast cancer patients. Researchers, however, have yet to investigate treatment responses therein on the whole exome level. We performed whole exome analysis to characterize the genomic landscape of extreme responders among metastatic breast cancer patients. Clinical samples were obtained from breast cancer patients who showed exceptional responses...
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