Article
Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.
Frontiers in endocrinology - 1 Jan 2024
Bai Chao, Yang Wenwen, Qi Guangwei, Yang Liuyu, Wu Qingrui, Peng Jieguang, Wang Ning, Liu Tao
Abstract excerpt
Objective: Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. While multiple studies have indicated changes in the expression of specific matrix metalloproteinases (MMPs) in patients with DN, and basic research has reported the impact of MMPs on DN, there is a lack of systematic research and the causal relationship...
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