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Article

Identification of biomarkers in diabetic neuropathy: a Mendelian randomization and bioinformatics analysis.

Frontiers in immunology - 1 Jan 2026

Li Jiannan, Yu Yue, Zhu Hongming, Chen Sibing, Liu Yanxi, Zhang Te

Abstract excerpt

Background: This study elucidated several plasma proteins that are causally linked to the risk of diabetic neuropathy (DN), offering novel insights into the protein-mediated DN pathogenesis and potential targets for therapeutic intervention. Methods: We employed Mendelian randomization (MR) utilizing genome-wide association study (GWAS) data to evaluate the causal effects of 4,907 proteins on DN. We retrieved a...

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Identifiers

PMID: 42125665
DOI: 10.3389/fimmu.2026.1793571
PMCID: PMC13158061

Genes

HSPB1
KRT14
SFN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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