Prevalence of resistance-associated substitutions and phylogenetic analysis of hepatitis C virus infection in Russia.

doi:10.1016/j.ijid.2021.09.041

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Article

Prevalence of resistance-associated substitutions and phylogenetic analysis of hepatitis C virus infection in Russia.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Dec 2021

Isakov Vasily, Hedskog Charlotte, Wertheim Joel O, Hostager Reilly E, Parhy Bandita, Schneider Adriano De Bernardi, Suri Vithika, Mo Hongmei, Geivandova Natalia, Morozov Vyacheslav, Bessonova Elena, Gankina Natalya, Zhdanov Konstantin, Abdurakhmanov Dzhamal, Svarovskaia Evguenia

Abstract excerpt

OBJECTIVES: Due to limited hepatitis C virus (HCV) sequence availability from patients in Russia, the relationship between subtypes and baseline resistance-associated substitutions (RAS) to direct antiretroviral treatment outcome is not fully understood. METHODS: Deep sequencing of HCV NS3, NS5A, and NS5B sequences was performed on plasma HCV samples from 412 direct-acting antiviral (DAA)-naïve patients from...

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PMID: 34560266
DOI: 10.1016/j.ijid.2021.09.041

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