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High-Resolution Whole-Genome DNA Methylation Revealed Unique Signatures of Painful Diabetic Neuropathy

8 Jan 2025

Abstract excerpt

The aim of this work was to describe the DNA methylation signature and identify genes associated with neuropathic pain in type 2 diabetes mellitus. We analyzed two independent cohorts: PROPGER, which comprised 72 patients with painful and 67 with painless diabetic neuropathy recruited at the German Diabetes Center in Düsseldorf, and PROPENG, which comprised 27 patients with painful and 65 with painless diabetic...

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Hereditary Neurological Disorders
Neurological diseases and metabolism
Pain Mechanisms and Treatments

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39774670
DOI: 10.2337/db24-0930

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