Article

DNA methylation supports accelerated biological age in Type 2 Diabetes which can be reversed with pharmacological treatments: Retrospective Cohort Study

2022-09-17

Abstract excerpt

<h4>Background</h4> Biological age (BA) closely depicts age-related changes at a cellular level. Type 2 Diabetes mellitus (T2D) accelerates BA when calculated using clinical biomarkers. However, there is a large spread of individual BA within these groups and it is unclear what clinical biomarkers correlate with different speeds of aging and whether pharmacological treatment of diabetes alter BA. We hypothesized...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 76e5832e-8fa1-5832-9025-f2c168468853
DOI: 10.1101/2022.09.14.507908

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

DNA methylation supports accelerated biological age in Type 2 Diabetes which can be reversed with pharmacological treatments: Retrospective Cohort StudyDOI 10.1101/2022.09.14.507908Read

DNA Methylation GrimAge and Incident Diabetes: The Coronary Artery Risk Development in Young Adults (CARDIA) StudySemantic proximity Read

DNA methylation age calculators reveal association with diabetic neuropathy in type 1 diabetesSemantic proximity Read

Epigenetics of Aging in Mammals: Mechanistic Foundations and Intervention Effects on DNA Methylation–Based Aging BiomarkersSemantic proximity Read

Dynamic DNA Methylation During Aging: A “Prophet” of Age-Related OutcomesSemantic proximity Read

Effect of Modifiable Lifestyle Factors on Biological AgingSemantic proximity Read

The Potential Use of DNA Methylation Biomarkers to Identify Risk and Progression of Type 2 DiabetesSemantic proximity Read

DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal functionSemantic proximity Read

Association of accelerated phenotypic aging, genetic risk, and lifestyle with progression of type 2 diabetes: a prospective study using multi-state modelSemantic proximity Read

Epigenetic Clock: DNA Methylation as a Marker of Biological Age and Age-Associated DiseasesSemantic proximity Read

A toolkit for quantification of biological age from blood-chemistry and organ-function-test data: BioAgeSemantic proximity Read

The Sociodemographic and Lifestyle Correlates of Epigenetic Aging in a Nationally Representative U.S. Study of Younger AdultsSemantic proximity Read

Effect of Metformin on the Epigenetic Age of Peripheral Blood in Patients With Diabetes Mellitus (DM)Semantic proximity Read