Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevalence of Duffy null and its impact on hydroxyurea in young children with sickle cell disease in the United States

10 Mar 2024

Abstract excerpt

Consistent with studies showing a high prevalence of the Duffy null phenotype among healthy Black Americans, this retrospective study found that Duffy null was present in >75% of a young and contemporary cohort of children with sickle cell disease (SCD) in the United States. Despite the potential for this phenotype to impact absolute neutrophil counts, hydroxyurea (HU) dosing, and outcomes, it was not associated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood groups and transfusion
Share to Hemoglobinopathies and Related Disorders
Share to Iron Metabolism and Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38462769
DOI: 10.1002/pbc.30945

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence of Duffy null and its impact on hydroxyurea in young children with sickle cell disease in the United StatesPMID 38462769Read ↗

Prevalence of Duffy null and its impact on Hydroxyurea dosing in children with sickle cell diseaseSemantic proximity Read ↗

Absolute neutrophil count nadir in healthy pediatric patients with the Duffy-null phenotype.Semantic proximity Read ↗

Role of Duffy-Negative Phenotype in Pediatric Sickle Cell Population.Semantic proximity Read ↗

Characterization of the phenotypic consequences of the Duffy-null genotypeSemantic proximity Read ↗

Absolute neutrophil count by Duffy status among healthy Black and African American adultsSemantic proximity Read ↗

White blood cell ranges and frequency of neutropenia by Duffy genotype status.Semantic proximity Read ↗

Duffy-Null Phenotype-Associated Neutropenia is the Most Common Etiology for Leukopenia/Neutropenia Referrals to a Tertiary Children's Hospital.Semantic proximity Read ↗

Multinational Assessment of Absolute Neutrophil Counts and White Blood Cell Counts Among Healthy Duffy Null AdultsSemantic proximity Read ↗

Diversity of variant alleles encoding Kidd, Duffy, and Kell antigens in individuals with sickle cell disease using whole genome sequencing data from the NHLBI TOPMed Program.Semantic proximity Read ↗

Lack of Duffy antigen expression is associated with organ damage in patients with sickle cell disease.Semantic proximity Read ↗

Emerging science of hydroxyurea therapy for pediatric sickle cell disease.Semantic proximity Read ↗

The Duffy-null genotype and risk of infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.